Opportunity Information: Apply for PAR 23 194

The Substance Use/Substance Use Disorder Dissertation Research Award (R36, Clinical Trials Not Allowed) is a National Institutes of Health funding opportunity from the National Institute on Drug Abuse (NIDA) designed to help doctoral candidates finish their dissertation research in areas related to substance use and substance use disorders. The core purpose is to provide up to two years of support so advanced doctoral students from a wide range of academic disciplines can complete a clearly defined dissertation project that strengthens the evidence base around substance use, addiction, prevention, treatment, recovery, and related public health and behavioral outcomes. By focusing on dissertation-stage researchers, the program is meant to act as an early on-ramp into the substance use and addiction research field, helping build a strong pipeline of new investigators.

Projects supported under this award are expected to align closely with NIDA priorities, either through NIDA's published funding priorities or through the institute's strategic planning framework. In practice, that means the dissertation research should fit within NIDA's mission-driven areas, such as understanding the causes and consequences of substance use, improving prevention and treatment approaches, addressing overdose and drug-related harms, studying services and systems that deliver care, and examining how substance use intersects with mental health, social factors, and health disparities. The award is specifically labeled "Clinical Trials Not Allowed," which means applicants must propose research that does not meet NIH's definition of a clinical trial; the work can still be rigorous and applied, but it cannot involve prospectively assigning human participants to an intervention to evaluate health-related outcomes.

A major emphasis of this opportunity is workforce development, including strengthening diversity in the substance use research workforce. Applications are particularly encouraged from doctoral candidates who would contribute to broadening representation in research, consistent with NIH's stated interest in diversity (NOT-OD-20-031). The intent is not only to fund individual projects, but also to expand who is conducting substance use research, bringing in perspectives and expertise from different backgrounds, disciplines, and communities, and ultimately improving the relevance and reach of research findings.

Eligibility is broad on the organizational side, reflecting NIH's typical range of applicant institutions. Eligible applicants include many types of U.S.-based organizations and governments, such as public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses) and small businesses, as well as state, county, city/township, and special district governments, independent school districts, and public housing authorities/Indian housing authorities. Federally recognized Native American tribal governments are eligible, as are tribal organizations that are not federally recognized. The announcement also highlights additional categories of eligible applicant organizations that NIH particularly calls out, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the opportunity places clear limits on foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply as the applicant organization, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components, as NIH defines them in the NIH Grants Policy Statement, are allowed, meaning a U.S.-based applicant may be able to include certain well-justified foreign elements in the research (for example, collaborations or specific research activities abroad) if they meet NIH policy requirements.

Administrative details from the source listing identify this as a discretionary grant program (funding instrument type: Grant) within the Education and Health activity categories and associated with CFDA number 93.279. The funding opportunity number is PAR-23-194, created June 15, 2023, with an original closing date of September 7, 2026. The listing does not specify an award ceiling or the expected number of awards in the provided fields, so applicants generally need to consult the full FOA text and NIH budget guidance for the R36 mechanism to understand allowable costs, budget structure, and any institute-specific expectations.

  • The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Substance Use/Substance Use Disorder Dissertation Research Award (R36 Clinical Trials Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279.
  • This funding opportunity was created on 2023-06-15.
  • Applicants must submit their applications by 2026-09-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
Apply for PAR 23 194

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